Experimental strategies for research on multiple chemical sensitivity.
نویسندگان
چکیده
منابع مشابه
Experimental strategies for research on multiple chemical sensitivity.
Skepticism about the validity of the multiple chemical sensitivity (MCS) syndrome stems in part from the lack of supporting experimental data. Performing the relevant experiments requires investigators to take account of broad variations in sensitivity and the need to establish reproducibility. The research approach best suited for MCS studies is the single-subject design. In contrast with conv...
متن کاملResearch on Multiple Chemical Sensitivity ( MCS )
This document lists citations for peer-reviewed journal articles that support a physiological basis for MCS. Disruption of the blood-brain barrier and neuronal cell death in cingulate cortex, dentate gyrus, thalamus, and hypothalamus in a rat model of Gulf-War syndrome. combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alt...
متن کاملMultiple Chemical Sensitivity
OBJECTIVE Systematic bibliography analysis of about the last 17 years on multiple chemical sensitivity (MCS) was carried out in order to detect new diagnostic and epidemiological evidence. The MCS is a complex syndrome that manifests as a result of exposure to a low level of various common contaminants. The etiology, diagnosis, and treatment are still debated among researchers. METHOD Queryin...
متن کاملMultiple Chemical Sensitivity: Toxicological and Sensitivity Mechanisms
Cases of multiple chemical sensitivity (MCS) are reported to be initiated by seven classes of chemicals. Each of the seven acts along a specific pathway, indirectly producing increases in NMDA activity in the mammalian body. Members of each of these seven classes have their toxicant responses lowered by NMDA antagonists, showing that the NMDA response is important for the toxic actions of these...
متن کاملOlfaction and multiple chemical sensitivity.
In this paper, a description of olfactory anatomy is presented, followed by a brief review of modern procedures for testing olfactory function. Information from the sole study which has quantitatively examined olfactory function in patients with apparent multiple chemical sensitivity (MCS) is presented. In essence, this study suggests that MCS is associated with increased nasal airflow resistan...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1997
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.97105s2487